10 best places to visit in South America: most beautiful cities
When it comes to the best places to visit in South America, the continent’s capital cities truly shine. Brimming with culture and offering a varied mix of cityscapes, if you’re planning a holiday to South America, these cities deserve a spot on your itinerary. From the soaring skyscrapers of central Santiago to the tropical beaches of Rio de Janeiro, here’s our pick of the most beautiful South American cities.
1. Buenos Aires, Argentina
The capital of Argentina, Buenos Aires is one of South America’s top destinations. To truly experience Argentinian culture, a visit to Buenos Aires is a must. This is a city of contrasts—where the elegant architecture of Plaza de Mayo and Casa Rosada sits alongside the colourful neighbourhoods of La Boca and San Telmo.
The birthplace of Tango, the city exudes a romantic, continental atmosphere. With its diverse population and thriving food scene, Buenos Aires is often dubbed the ‘Paris of South America’.
2. Rio de Janeiro, Brazil
Known as the ‘Marvellous City’, Rio de Janeiro is the sun-soaked, samba-filled heart of Brazil. Famed for its golden beaches and watched over by the imposing Christ the Redeemer statue, Rio offers something for everyone. Whether you’re after lively nightlife, sunbathing, or hiking through lush forests, Rio delivers.
The city is world-renowned for Carnival, the largest celebration on the planet. But the festive vibe can be found year-round—locals gather on Ipanema Beach or dance the samba in the Lapa district. Without doubt, one of the most captivating cities in South America.
3. La Paz, Bolivia
Nestled in the Andes, La Paz is a city of dramatic landscapes and rich heritage in Bolivia. Its unique setting and breathtaking views only add to its appeal. From peaceful plazas to winding cobbled streets, there’s much to explore. At the heart of the city, modern skyscrapers rise against the mountainous backdrop.
As the world’s highest capital, standing at 3,650 metres above sea level, it’s a destination like no other. Don’t miss a ride on the city’s iconic cable cars, which link its highest neighbourhoods—perhaps the most scenic public transport system in the world!
4. Santiago, Chile
Around 40% of Chile’s population lives in Santiago, and it’s easy to see why. As the country’s cultural and economic hub, the city boasts excellent museums, theatres, eateries and vibrant shopping streets. Its lively nightlife can be found spilling out of pavement cafés and buzzing bars.
Santiago makes an ideal base for exploring Chile’s Pacific coast or the mighty Andes. From colonial Central Santiago to artsy Bellavista and sleek Sanhattan, each district offers its own charm. It’s a beautiful place to discover Chilean culture.
5. Cusco, Peru
A living museum, Cusco is among South America’s most historic and mesmerising cities. With a blend of colonial charm and ancient Inca heritage, it’s an essential stop on any tour of Peru. Time seems to stand still in this enchanting city.
Sitting at 3,400 metres above sea level, Cusco was once the capital of the Inca Empire. Surrounded by the Andes, it’s a wonderful place to wander through atmospheric squares, steep alleys and watch locals in traditional dress go about their day.
6. Cartagena de Indias, Colombia
Known as the ‘Queen of the Caribbean Coast’, Cartagena is one of South America’s most beautiful cities. A vibrant, colourful destination, it blends well-preserved colonial architecture with cultural charm. Its Old Town is a UNESCO World Heritage Site, and its iconic Palenquera fruit sellers—balancing bowls of tropical fruits—are a symbol of the city.
Cartagena’s Caribbean beaches appeal to sunseekers looking for a touch of luxury. Without question, it’s one of the top places to visit in South America. Be sure to include it on your next adventure to Colombia.
7. Quito, Ecuador
Perched high in the Andean foothills at 2,850 metres above sea level, Quito is among South America’s most scenic capitals. The capital of Ecuador boasts one of the best-preserved historic centres in Latin America—earning it UNESCO World Heritage status. Stroll its cobbled streets, admire colonial churches and soak up the lively squares.
Quito’s dramatic setting between volcanoes provides breathtaking panoramas from every angle. Don’t miss the chance to stand on the Equator line at the “Middle of the World” monument just outside the city. It’s also the perfect launchpad for exploring Ecuador’s diverse natural wonders—from the Amazon to the Galápagos Islands.
8. Montevideo, Uruguay
Often overlooked by travellers, Montevideo is a hidden gem among South America’s top cities. Uruguay’s capital exudes a relaxed vibe that contrasts with the intensity of its larger neighbours. The city hugs the Río de la Plata, with miles of lovely seafront promenades known as the Rambla.
Montevideo’s architecture reflects a mix of colonial heritage, Art Deco flair and contemporary design. The historic Ciudad Vieja (Old Town) is full of charming squares and colourful facades, while Mercado del Puerto offers a taste of Uruguay’s legendary grilled meat. With its easy-going pace, welcoming locals, and superb cuisine, Montevideo is an ideal spot to unwind and explore.
9. Medellín, Colombia
Once infamous for its turbulent history, Medellín has undergone an incredible transformation to become one of the top cities to visit in South America. Known as the “City of Eternal Spring” thanks to its mild, year-round climate, Medellín lies in a lush valley surrounded by green hills. The city is now a model of innovation, with cable cars and outdoor escalators linking its once-isolated communities.
Public spaces are filled with art—especially the oversized sculptures of local artist Fernando Botero. With friendly locals (known as Paisas), a lively cultural scene, and growing foodie hotspots, Medellín is gaining popularity. The annual Feria de las Flores (Flower Festival) in August floods the city with colour and celebration.
10. Sucre, Bolivia
Often referred to as “The White City” for its gleaming colonial facades, Sucre is a strong contender for the title of South America’s prettiest city. Bolivia’s constitutional capital sits at a comfortable altitude of 2,800 metres, offering milder weather than La Paz. The historic centre is a UNESCO World Heritage Site, home to grand churches, shady courtyards, and peaceful streets.
Sucre’s relaxed rhythm makes it easy to soak up its charm. The city also boasts excellent museums that delve into Bolivia’s indigenous culture and revolutionary history. It’s a great place to learn Spanish, explore nearby villages, or simply slow down and take in the scenery.
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